Diagnosis of Laryngopharyngeal Reflux Among Globus Patients

Globus is the state of feeling a continuous sensation of a lump or tightness in the throat. It accounts for 4% to 10% of the complaints of patients who visit otolaryngology clinics, and is reported to be on the increase in populations recently. However, the etiology is still unclear, which makes it difficult for diagnosis and treatment. Nowadays, of the various causes of globus, gastroesophageal reflux is reported to account for 23% to 68%, signifying its importance as a cause that should be diagnosed properly among globus patients.

Diagnostic methods for laryngopharyngeal reflux (LPR) include 24-hour double-probe ambulatory pH monitoring, gastroesophagogram, and gastroesophageal endoscopy. But these are not easy to use in clinics, so there is a need for a tool that is not only less invasive but also highly sensitive and specific.  Recently, other tools based on physical findings and symptoms such as reflux finding score (RFS) and reflux symptom index (RSI) have been tried in some clinics and their simple, economic, and noninvasive characteristics were reported.

Read: Diagnosis of Laryngopharyngeal Reflux Among Globus Patients


Kyung Hoon Park, MD, Sun Myung Choi, MD, Soon UK Kwon, MD, Sang Won Yoon, MD, and Seon UK Kim, MD, Seoul, Korea

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